A disorder characterized by rheumatoid arthritis , an enlarged spleen , a decreased white blood cell count , and recurrent infection.
Causes, incidence, and risk factors
The cause of Felty’s syndrome is unknown. It is a variant of rheumatoid arthritis and is more common in people who have had rheumatoid arthritis for a long time. People with this syndrome suffer from an increased incidence of infection associated with the low white blood cell count .
Signs and tests
A physical examination shows an enlarged spleen , and may also show an enlarged liver or enlarged lymph nodes . Joint findings are typical of rheumatoid arthritis . A CBC may show decreased neutrophil count.
Treatment
People with this syndrome are usually already under treatment for rheumatoid arthritis . Splenectomy (removal of the spleen) may improve the white cell count and the susceptibility to infections.
Expectations (prognosis)
Progression of rheumatoid arthritis is likely. Some people benefit from splenectomy .
Complications
Recurrent infections may develop.
Calling your health care provider
Call for an appointment with your health care provider if symptoms of this disorder develop.